Week 5 NFL odds, spreads, totals, betting lines, for all 16 games, including Buccaneers-Cowboys, Bears-Packers

NFL Week 5 opens when the Dallas Cowboys host the Tampa Bay Buccaneers on Thursday Night Football. Dallas is favored by 9.5 points, according to the latest Week 5 NFL odds. Other notable Week 5 NFL spreads include Eagles vs. Jaguars (-6.5) in London, Bears vs. Packers (+3), 49ers vs. Seahawks (-3) and Bills vs. Rams (-2.5). Bet on every Week 5 NFL game with the latest DraftKings promo code, where new users get $150 in bonus bets after making a $5 wager: 

Below you’ll find the NFL betting odds for every Week 5 matchup. You can find the SportsLine Projection Model’s NFL betting advice for Week 5 here. Trade $25+ at Kalshi using the best Kalshi promo code CBSSPORTS55 and get $55 as a sign-up bonus:

** Odds provided by DraftKings are subject to change **

Thursday, Oct. 8

Dallas Cowboys vs. Tampa Bay Buccaneers

Spread: Cowboys -9.5
Moneyline: Cowboys (-476), Buccaneers (+380)
Total: 47.5   

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Sunday, Oct. 11

Jacksonville Jaguars vs. Philadelphia Eagles

Spread: Jaguars -6.5
Moneyline: Jaguars (-275), Eagles (+240)
Total: 42.5  

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Green Bay Packers vs. Chicago Bears

Spread: Bears -3
Moneyline: Packers (+136), Bears (-142)
Total: 45.5  

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Tennessee Titans vs. Houston Texans

Spread: Texans -7
Moneyline: Titans (+275), Texans (-323)
Total: 39.5  

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Miami Dolphins vs. Cincinnati Bengals

Spread: Bengals -7.5
Moneyline: Dolphins (+310), Bengals (-345)
Total: 42.5  

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New England Patriots vs. Las Vegas Raiders

Spread: Patriots -3.5
Moneyline: Patriots (-192), Raiders (+176)
Total: 45.5  

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New Orleans Saints vs. Minnesota Vikings

Spread: Vikings -1.5
Moneyline: Saints (+102), Vikings (-118)
Total: 42.5   

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New York Jets vs. Cleveland Browns

Spread: Jets -2.5
Moneyline: Jets (-128), Browns (+110)
Total: 39.5   

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Pittsburgh Steelers vs. Indianapolis Colts

Spread: Steelers -2.5
Moneyline: Steelers (-135), Colts (+116)
Total: 44.5  

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Washington Commanders vs. New York Giants

Spread: Commanders -3
Moneyline: Commanders (-166), Giants (+154)
Total: 43.5  

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Los Angeles Chargers vs. Denver Broncos

Spread: Broncos -3.5
Moneyline: Chargers (+156), Broncos (-185)
Total: 42.5   

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Arizona Cardinals vs. Detroit Lions

Spread: Lions -4.5
Moneyline: Cardinals (+198), Lions (-225)
Total: 54.5   

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Seattle Seahawks vs. San Francisco 49ers

Spread: Seahawks -3
Moneyline: Seahawks (-148), 49ers (+138)
Total: 47

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Atlanta Falcons vs. Baltimore Ravens

Spread: Falcons -2.5
Moneyline: Falcons (-155), Ravens (+130)
Total: 44

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Monday, Oct. 12

Los Angeles Rams vs. Buffalo Bills

Spread: Rams -2.5
Moneyline: Rams (-152), Bills (+135)
Total: 54.5  

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